REUTLINGEN, Germany, Sept. 10 (UPI) -- German scientists
say they've created a breed of pea seeds that contain antibodies
against coccidiosis, a disease caused by a parasite that attacks
chickens.
The Novoplant GmbH researchers, led by Sergej Kiprijanov of
the German biotechnology company Affitech, developed the genetically
modified seeds.
"There are a few major issues precluding the use of
monoclonal antibodies for passive immunization of chickens against
infectious diseases, primarily the costs of antibody production and
treatment," Kiprijanov said. "Treatment costs are high because
antibodies must normally be given intravenously; otherwise they are
destroyed in the animal's gut. By expressing the antibodies inside
pea seeds, they are protected from this degradation, allowing our
system to dramatically reduce treatment costs."
The researchers said they found infected chickens fed the
antibody-containing pea seeds that were shredded into their feed
were significantly less likely to contract coccidiosis than chickens
fed ordinary pea seeds in their fodder.
"Compared with methods of active vaccination, the passive
immunization strategy is an easy and non-invasive method to use
in commercial settings," Kiprijanov said. "The cost of production is
comparatively low, utilizing current agriculture technologies, and
the strategy can be used in combination with other anti-parasitic
agents."
The study appears in the journal BMC Biotechnology.